Name: Dr. Sachinkumar S. Pawar

Designation: Senior Scientist

Date of Birth: 19.08.1981

Area of Specialization: Molecular basis of thermotolerance and immune response in livestock

Email Id: ss.pawar@icar.gov.in; sachinndri@gmail.com

Mobile: +91-7721809906; Phone: 02112-254057, Fax: 02112-254056

Education

Professional History

Publications

Published more than 20 research papers, 10 review papers, 5 technical bulletins and 2 book chapters. h-index 10, i10-index 11 with more than 282 citations in international literature.

Publication’s List-

1. Pawar S.S., Meshram C.D., Singh N.K., Saini M., Mishra B.P., Gupta P.K. (2017) EvaGreen-based Multiplex Real-time PCR Assay for Rapid Differentiation of Wild-Type and Glycoprotein E-Deleted Bovine Herpesvirus-1 Strains. Animal Biotechnology. Vol. 28 (4): 248-252.
2. Pawar S.S., Meshram C.D., Singh N.K., Sonwane A.A., Saini M., Rautmare S.S., Muglikar D.M., Mishra B.P., Gupta P.K. (2014) Rapid detection of bovine herpesvirus-1 in bovine semen by loop mediated isothermal amplification (LAMP) assay. Archives of Virology. Vol. 159 (4): 641-648.
3. Pawar S.S., Meshram C.D., Singh N.K., Saini M., Mishra B.P., Gupta P.K. (2014) Development of a SYBR Green I based duplex real-time PCR for detection of bovine herpesvirus-1 in semen. Journal of Virological Methods. Vol. 208: 6-10.
4. Pawar S.S., Meshram C.D., Singh N.K., Saini M., Mishra B.P., Gupta P.K. (2015) Loop-Mediated Isothermal Amplification for Rapid Detection and Differentiation of Wild-Type Bovine Herpesvirus-1 and Glycoprotein E-Deleted Marker Vaccine Strain. Animal Biotechnology. Vol. 26 (4): 268-272.
5. Sajjanar B., Rajib Debb, Raina S.K., Pawar S.S., Brahmane M.P., Nirmale A.V., Kurade N.P., Reddy G.B.M., Bal S.K., Singh N.P. (2017) Untranslated regions (UTRs) orchestrate translation reprogramming in cellular stress responses. Journal of Thermal Biology. Vol. 65: 69-75.
6. Singh N.K., Meshram C.D., Sonwane A.A., Dahiya S.S., Pawar S.S., Chaturvedi V.K., Saini M., Singh R.P., Gupta P.K. (2014) Protection of Mice against lethal rabies virus challenge using short interfering RNAs (siRNAs) delivered through lentiviral vector. Molecular Biotechnology. Vol. 56 (2): 91-101.
7. Subramaniam S., Pattnaik B., Sanyal A.,  Mohapatra J.K., Pawar S.S., Sharma G.K., Das B., Dash B.B. (2013) Status of Foot and Mouth Disease in India. Transboundary and Emerging Diseases. Vol. 60 (3): 197-203.
8. Meshram C.D., Singh N.K., Sonwane A.A., Pawar S.S., Mishra B.P.,  Chaturvedi V.K., Saini M., Singh R.P., Gupta P.K. (2013) Evaluation of single and dual siRNAs targeting rabies virus glycoprotein and nucleoprotein genes for inhibition of virus multiplication in vitro.  Archives of Virology. Vol. 158 (11): 2323-2332.
9. Gupta P.K., Sonwane A.A., Singh N.K., Meshram C.D., Dahiya S.S., Pawar S.S., Gupta S.P., Chaturvedi V.K., Saini M. (2012) Intracerebral delivery of small interfering RNAs (siRNAs) using adenoviral vector protects mice against lethal peripheral rabies challenge. Virus Research. Vol. 163 (1): 11-18.
10. Mohapatra J.K, Saravanan S., Pandey L.K, Pawar S.S., De A., Das B., Sanyal A., Pattnaik B.  (2011) Phylogenetic structure of serotype A foot and mouth disease virus: Global diversity and the Indian perspective. Journal of General Virology. Vol. 92 (4): 873-879. 

Technologies/Products/Patents

Technologies

• Developed SYBR Green I duplex real-time PCR for sensitive detection of BoHV-1 in bovine semen (2014).
• Developed Loop-mediated Isothermal Amplification (LAMP) for user friendly and rapid detection of BoHV-1 in bovine semen with naked eyes within 90 min (2014).
• Developed Loop-mediated isothermal amplification (LAMP) for user friendly differentiation of gE-deleted BoHV-1 from wild-type virus (2015).
• Developed EvaGreen-based multiplex real-time polymerase chain reaction (EGRT-PCR) for rapid differentiation of wild-type and glycoprotein E-deleted BoHV-1 strains (2017). 
• Developed Glycoprotein E (gE) gene deleted mutant of infectious bovine rhinotracheitis (IBR) virus as a vaccine candidate strain for IBR DIVA vaccine in India (2012).

Patents

• Gupta P.K, Pawar S.S., Saini M., Prusty B.R., Mishra B.P. Construction of glycoprotein E (gE) gene-deleted mutant of infectious bovine rhinotracheitis (IBR) virus Indian strain for DIVA-based marker vaccine. (Patent Application No. 1858/DEL/2014).
• Gupta P.K, Pawar S.S., Meshram C.D., Mishra B.P. A rapid, sensitive and user-friendly visual LAMP assay for detection of infectious bovine rhinotracheitis (IBR) virus in bovine semen. (Patent Application No. 627/DEL/2012).

Awards/Fellowships/Recognitions

• “Best Veterinary Research Worker Award” by KNP Vet Alumni Association (2018).
• Editor board member of Advances in Animal and Veterinary Sciences (2015-16).
• Editor board member of Advances in Zoology (2015-16).
• Awarded ICAR- NET  in Biotechnology (Animal Science) by Indian Council of Agricultural Research, New Delhi (2008).
• Awarded CSIR- NET  in Life Science by Council of Scientific & Industrial Research, New Delhi (2005).
• Awarded IVRI Scholarship for Ph.D. degree programme by Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh (2006).
• Awarded Institute Scholarship for M.V.Sc. degree programme by National Dairy Research Institute, Karnal, Haryana (2004). 

Member of Professional bodies​

1. Life Member of Society for Agricultural Research on Abiotic Stress (SARAS)